Incorporation of 1-C14-arachidonic acid into linoleic acid in liver phospholipid of rats with deficiency of fat and vitamin B6.

It has been known that linoleic acid is converted to arachidonic acid in the body, and its process has gradually become clear. However, it is still unknown to what compound arachidonic acid is changed. According to the report of Davis et all) arachidonic acid labeled with C14 is incorporated into docosapentaenoic acid (22:5•¢)4.7.10.13.16 in the body of albino rats. The author has previously reported2),3) that arachidonic acid is converted to linoleic acid in the phospholipid of albino rat liver and these two acids appear to form a cycle. Extending these results further, we have confirmed the incorporation of 1-C14-arachidonic acid into linoleic acid in the phospholipid of albino rat liver, as reported below.